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ECB Governing Council member Koch said threatening tariffs will accelerate inflation in the United States.European Central Bank President Christine Lagarde: Central banks cannot always be the ones to deal with debt problems.January 21 – As tensions escalate between the traditional allies, the US and UK, US Treasury Secretary Bessenter stated that the US-UK trade agreement has encountered some “minor problems.” Speaking at a World Economic Forum event, Bessenter said that the UK initially “took the initiative” to sign a “model” trade agreement with the US. Bessenter said, “I think we are still negotiating, but there are some issues with the trade agreement. I believe the Starmer government will continue to move forward with the negotiations.” The two countries signed a trade agreement last year that included reducing punitive tariffs imposed by the US on British cars and steel. However, Trump subsequently threatened to impose a 10% tariff on the UK over Greenland, and this week he also criticized the Starmer government for abandoning the Chagos Islands agreement.The governor of Central Bank Indonesia stated that global factors include geopolitical tensions, US tariffs, high US Treasury yields, and a reduced probability of a Federal Reserve rate cut.January 21st - According to foreign media reports, US Treasury Secretary Bessenter stated on Wednesday that he is not worried about the sell-off of US Treasury bonds and linked it to the volatility of Japanese government bonds, saying he has been in contact with his Japanese counterparts and assured them that they will take measures to stabilize the market. Denmarks position on US Treasury bonds is irrelevant, just like the country itself. He called on European allies to understand that Greenland needs to be part of the United States and hoped they would sit back and wait for President Trumps speech. According to the schedule released by the World Economic Forum, Trump is scheduled to deliver a public speech in Davos at 21:30 Beijing time. However, Bessenter indicated that President Trump would arrive in Davos approximately three hours late.

AstraZeneca's nasal spray vaccine trial for COVID experiences a setback

Charlie Brooks

Oct 11, 2022 11:23

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Tuesday, attempts by researchers from Oxford University and AstraZeneca (NASDAQ:AZN) Plc to manufacture a nasal-spray version of their jointly developed COVID-19 injection were hindered by the failure of first human tests to give the required degree of protection.


During the first of generally three phases of clinical testing, a minority of trial participants had an antibody response in their respiratory mucous membranes, according to a statement released by the University of Oxford on Tuesday.


In addition, the immune response measured in the blood was weaker than that caused by an arm injection.


Researchers from throughout the world have high hopes for nasal spray vaccinations against the coronavirus, as it is predicted that the method could prevent infection and illness by stimulating an immune response directly in the airways, where the virus enters the body.


In addition, the method would be less painful and easier to administer than injections.


In India and China, regulators have previously authorized the administration of drugs via the airways.


Last month, India's health minister approved Bharat Biotech's COVID-19 nasal spray vaccine, while China's medicines regulator approved CanSino Biologics Inc's COVID-19 inhaled vaccine on an emergency basis.


CanSino has said that its nebuliser-delivered vaccine can develop robust immunity to successfully restrict disease, but Bharat's trial findings are not yet available.


The British study included 30 unvaccinated patients and 12 volunteers who had previously undergone a normal two-dose immunization course.


In this study, the nasal spray did not perform as well as anticipated, according to Sandy Douglas, the trial's primary investigator at the Jenner Institute of Oxford University.


She went on to say, "We believe that delivery of vaccinations through the nose and lungs remains a viable option, but this study suggests that there will be challenges in making nasal sprays a reliable alternative."


During the AstraZeneca-funded trial, no severe adverse events or safety concerns were reported, according to the release.

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